Current Issue : April - June Volume : 2018 Issue Number : 2 Articles : 3 Articles
Ocimum sanctum (Tulsi) is reported to be effective against common ailments such as cough, cold, asthma, ulcers. It is also reported for use in the treatment for arthritis, heart disorders, sexually transmitted diseases, cancer, eye disorders, Alzheimer’s disease. Each part of Tulsi plant has bioactive constituents which show different pharmacological activities in different extracts. The several extracts such as aqueous, ethanolic, benzene are reported to show certain pharmacological activities for e.g. benzene extract of Tulsi leaves shows anti fertility effect, alcoholic extract of Tulsi leaves shows radio protectivity. The fixed oil from seeds of Tulsi plant shows anti pyretic activity. Literature reports animal models for anti-arthritic, anti-pyretic, neurocognitive, anti-asthmatic, hepatoprotectivity, anti-fertility activity and these are compiled in this review article along with the marketed formulations available in Indian market....
The main objective of this work was to evaluate the potential antidiabetic effect of Citrus grandis peel in alloxan induced diabetic rats. Diabetes was induced by injecting single dose administration of alloxan (150 mg/kg, i.p). The induction of diabetes was confirmed after 3 days of alloxan injection and the rats with fasting blood glucose levels were greater than 200 mg/dl were considered to be diabetic and used further for study. In the present study 30 rats were divided into 6 groups, each group containing 5 animals; non diabetic group, diabetic group, glibenclamide (10 mg/kg, p.o) treated group, Citrus grandis peel extract treated groups (100 mg/kg, 200 mg/kg, 400 mg/kg, p.o). Each extract was administrated orally daily for 14 days. On the last day, the blood was collected from all the groups of rats which have fasted overnight by puncturing the retro-orbital of the eye under mild ether anesthetic condition. The statistical data indicated that the different dose of Citrus grandis peel significantly decreases the level of fasting blood glucose level in alloxan induced in rats. Histopathological examination of heart indicated that the administration of Citrus grandis peel was showed significant decrease in necrotic lesions, perivascular oedema and infiltrations of cells as compared to diabetic rats. Our investigation has clearly indicated that ethanolic extract of Citrus grandis peel showed antihyperglycemic activity....
A primary advantage of botanicals is their complex composition consisting of collection of related compounds having multiple activities that interact for a greater total activity. The present work was based on the development of new antimicrobial and anthelmintic agents from natural sources. The antibacterial activity tested by cup plate method and anthelmintic activity tested on Indian earth worms, Pheretima posthuma. The maximum antibacterial activity of ethanolic extract of Terminalia arjuna leaves was exhibited against Proteus vulgaris and Eschericia coli while in other tested bacterial organisms, the maximum inhibition was observed with Staphylococcus aureus and then with Bacillus subtilis then Micrococcus luteus. When observed both gram positive and gram negative bacterial organisms the ethanolic extract of leaves of Terminalia arjuna was more active against gram negative species. The ethanolic extract of leaves of T. arjuna at 100 mg/ml showed paralysis of worms nearly equals to the standard drug concentration. The ethanolic extract of leaves of Terminalia arjuna showed that significant anthelmintic activity when compared to piperazine citrate (5 mg/ml)....
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